Medicine

Advancing ASO treatments from advancement to execution

.Contending enthusiasms.R.S., M.S., H.G. and also A.A.R. are coordinators of the 1M1M campaign. H.G. and A.A.R. are actually board of directors members and also R.S., M.S. and also A.A.R. are participants of the clinical consultatory committee of N1C. A.A.R. discloses job by LUMC, which has patents on exon-skipping technology, some of which has been actually licensed to BioMarin as well as consequently sublicensed to Sarepta. As co-inventor of a number of these patents, A.A.R. was actually allowed to an allotment of royalties. A.A.R. even more reveals functioning as impromptu specialist for PTC Therapeutics, Sarepta Rehabs, Regenxbio, Dyne Therapeutics, Lilly, BioMarin Pharmaceuticals Inc., Eisai, Entrada, Takeda, Splicesense, Galapagos, Sapreme, Italfarmaco as well as Astra Zeneca. Over the last 5 years, A.A.R. additionally did speaking with for Alpha Anomeric. A.A.R. also states registration of the scientific advisory boards of Eisai, Hybridize Therapies, Silence Rehabs, Sarepta Rehabs, Sapreme and also Mitorx. Over the last 5 years, A.A.R. was actually also a clinical advisory board participant for ProQR. Wage for A.A.R. u00e2 s consulting as well as suggesting activities is spent to LUMC. Before 5 years, LUMC likewise got speaker gratuity coming from PTC Therapeutics, Alnylam Netherlands, Italfarmaco and also Pfizer and also cashing for contract research coming from Sapreme, Eisai, Galapagos, Synaffix and Alpha Anomeric. Project financing is gotten from Sarepta Therapeutics as well as Entrada through unconstrained grants. H.G. possesses absolutely nothing to divulge in regard to the subject matters dealt with within this composition. Over the last 5 years, he has additionally received consultancy gratuity coming from UCB. M.S. got consultancy honoraria coming from Ionis, UCB, Prevail, Orphazyme, Biogen, Servier, Reata, GenOrph, AviadoBio, Biohaven, Zevra, Lilly as well as Solaxa in the past 5 years, all unconnected to today document. R.S. has nothing to disclose in relation to the topics covered in this particular document. She has actually obtained speaker and/or working as a consultant gratuity or financing additions from Abbvie, Bial, STADA as well as Everpharma over the last 5 years.

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